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First trimester fetal nuchal translucency

P P Pandya1, C Santiago, R J Snijders

  • 1Harris Birthright Research Center for Fetal Medicine, King's College Hospital Medical School, London, UK.

This review examines the development of a new method of screening for Down's syndrome based on the combination of fetal nuchal translucency thickness, maternal age and maternal serum biochemistry at 10-14 weeks of gestation. This method can potentially identify more than 80% of affected fetuses for a false-positive rate of less than 5%.

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