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Updated: Jul 7, 2026

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Published on: February 4, 2018
Tropheryma whippelii endocarditis confirmed by polymerase chain reaction
D Wendler1, E Mendoza, T Schleiffer
1Department of Pathology, General Hospital of Ludwigshafen/Rhein, Germany.
Abstract:
This report concerns a patient with cardiac manifestation of Whipple's disease. For the first time, the gene that encodes the 16s rRNA of Tropheryma whippelii was identified in a native aortic valve by means of a polymerase chain reaction technique. DNA amplification gives evidence of Tropheryma whippelii as a causative organism in infective endocarditis.
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