Related Experiment Videos
The epidemiology of benign prostatic hyperplasia and observations on concomitant hypertension
1Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy.
Insights
Benign prostatic hyperplasia (BPH) and hypertension are common in aging men. Further studies are needed to understand their association and develop early detection strategies for concurrent BPH and hypertension.
Area of Science:
- Gerontology
- Urology
- Cardiology
Background:
- Benign prostatic hyperplasia (BPH) and hypertension are prevalent, age-related conditions in men.
- BPH affects over 80% of men over 70 and 40% of men aged 50-64.
- Hypertension affects over 50% of men aged 65-74, with cardiovascular disease being a leading cause of death.
Purpose of the Study:
- To investigate the association between benign prostatic hyperplasia (BPH) and hypertension.
- To explore the frequency of concomitant BPH and hypertension.
- To identify opportunities for preventive strategies and early detection of these conditions.
Main Methods:
- Epidemiological studies were reviewed.
- Pathological and population data on BPH and hypertension prevalence were analyzed.
- Potential common etiologies, such as the sympathetic nervous system, were considered.
Main Results:
- Both BPH and hypertension are highly prevalent in aging men.
- Both conditions share some underlying etiological features, including sympathetic nervous system involvement.
- The frequency of concomitant BPH and hypertension and their specific associations require further investigation.
Conclusions:
- There is a need for further epidemiological research into the association between BPH and hypertension.
- Developing preventive strategies for early detection and treatment of concurrent BPH and hypertension is warranted.
- Understanding the interplay between these common age-related disorders can improve men's health outcomes.
Abstract:
Benign prostatic hyperplasia (BPH) and hypertension are highly prevalent, age-related disorders in men which place a considerable burden on healthcare resources worldwide. Evidence of pathological BPH can be found in over 80% of autopsies conducted in men over 70 years of age; around 40% of men aged 50-64 years have symptoms compatible with the disease. Population studies suggest that over 50% of people aged 65-74 years may be hypertensive, and that cardiovascular disease is a major cause of death worldwide. The continued ageing of the population means that more people are living to older ages; life expectancy for men is likely to exceed 80 years by the end of this century in some developed countries. While BPH and hypertension are apparently diverse disease processes, they have some features in common (e.g. underlying aetiology of the sympathetic nervous system). However, little else is known about any associations between the two or the frequency of concomitant disease. There are clearly opportunities for further epidemiologic studies and the development of preventive strategies aimed at the early detection and treatment of concomitant BPH and hypertension.