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Published on: August 9, 2012
Correlation between micturitional urethral pressure profile and pressure-flow criteria in bladder outlet obstruction
C E DuBeau1, M P Sullivan, E Cravalho
1Urology Division, Brockton/West Roxbury Veterans Administration Medical Center, Boston, Massachusetts, USA.
Purpose:
We correlate micturitional urethral pressure profilometry with pressure-flow diagnoses of outlet obstruction.
Materials And Methods:
Urodynamic evaluation was done of 86 consecutive men with voiding symptoms. Obstruction criteria were a micturitional urethral pressure profile (MUPP) gradient greater than 5 cm. water, Schäfer's linear passive urethral resistance relation (PURR) greater than grade 1 and Abrams-Griffiths nomogram.
Results:
Interpretable results were completed in 99% of the patients undergoing MUPP and 60% undergoing pressure-flow studies (p < 0.00001). MUPP diagnosis agreed with PURR (p = 0.0015) and Abrams-Griffiths nomogram results (p = 0.00004). MUPP gradients correlated well with PURR (r = 0.70, p < 0.00001). Using optimum cutoff values (11 cm. water), the sensitivity of MUPP was 83%, specificity 82% and positive predictive value 94%.
Conclusions:
MUPP correlates well with and yields interpretable results more often than pressure-flow studies.
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