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Molecular basis of 11q23 rearrangements in hematopoietic malignant proliferations

O A Bernard1, R Berger

  • 1U 301 Institut National de la Santé et de la Recherche Médicale (INSERM), Paris, France.

Genes, Chromosomes & Cancer
|June 1, 1995
PubMed

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Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...