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New knowledge in primary biliary cirrhosis
1School of Medicine, University of California, Davis, USA.
Hospital Practice (1995)
|August 15, 1995
Abstract:
The autoantibodies characteristic of the disease react against mitochondrial enzymes essential to the function of all body cells, yet the disease is highly focused on only one tissue: the epithelial lining of intrahepatic bile ductules. The explanation may lie in tissue-specific cell-surface expression of a triggering antigen.