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Bacillary angiomatosis

J G Batsakis1, J Y Ro, E E Frauenhoffer

  • 1Department of Pathology, University of Texas M. D. Anderson Cancer Center, Houston, USA.

The Annals of Otology, Rhinology, and Laryngology
|August 1, 1995
PubMed
Summary
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Rochalimaea henselae causes opportunistic infections like bacillary angiomatosis and cat-scratch disease in immunocompromised individuals. Further research is needed to understand why this bacterium produces distinct lesions in different conditions.

Area of Science:

  • Infectious Diseases
  • Immunology
  • Bacteriology

Background:

  • Acquired immunodeficiency syndrome (AIDS) and other immunosuppressive conditions lead to opportunistic infections.
  • Bacillary angiomatosis is a vasoproliferative disease often caused by Rochalimaea henselae, primarily affecting the skin but can become systemic.

Purpose of the Study:

  • To identify the causative agent of bacillary angiomatosis.
  • To investigate the relationship between bacillary angiomatosis and cat-scratch disease.

Main Methods:

  • Utilized molecular technology and epidemiologic studies.
  • Identified the bacterial agent responsible for bacillary angiomatosis.

Main Results:

  • Rochalimaea henselae was identified as the principal causative agent of bacillary angiomatosis.

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  • Rochalimaea henselae was also found to be responsible for most cases of cat-scratch disease.

    • Conclusions:

    • Rochalimaea henselae causes both bacillary angiomatosis and cat-scratch disease.
    • The reason for the differing histopathologic lesions caused by the same organism remains unknown.