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Regulation of NK cells through the 80-kDa TNFR (CD120b)

A T Mason1, D W McVicar, C A Smith

  • 1Laboratory of Experimental Immunology, NCI-FCRDC, Frederick, Maryland 21702-1201, USA.

Journal of Leukocyte Biology
|August 1, 1995
PubMed
Summary

Tumor necrosis factor receptor 80 (TNFR80) is crucial for natural killer (NK) cell activation. This receptor mediates signals for NK cell differentiation and enhanced cytotoxic activity when stimulated by TNF and IL-2.

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