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Reference values for fetal hemoglobin concentration in blood of steel-mill workers
M Stepniewski1, U Cieszkowska, J Pach
1Department of Toxicology Collegium Medicum, Jagiellonian University, Kraków, Poland.
Abstract:
The concentration of fetal hemoglobin (HbF) in blood of 195 healthy men and 39 women was measured by alkali denaturation method of Singer et al. Arithmetic mean in the group of men was 0.325% whereas in women it was 0.399%. The difference between the means was statistically significant. Frequency histograms showed two unlike subpopulations with wider span of values in women, different standardised skewness and kurtosis. Kolmogorov-Smirnoff test revealed a significant abnormality of both distributions. The data presented may serve for the comparison of HbF values obtained in persons living and working in similar microclimatic conditions.