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Characterization of the recognition site and diagnostic potential of an enterovirus group-reactive monoclonal
A Samuelson1, M Forsgren, M Sällberg
1Department of Immunology, Microbiology, Pathology and Infectious Diseases, Karolinska Institutet, Huddinge University Hospital, Sweden.
Clinical and Diagnostic Laboratory Immunology
|May 1, 1995
Abstract:
The epitope for a monoclonal antibody reactive against different enteroviruses was characterized. The epitope could be located to residues 40 to 48 of VP1, and the most-essential residues for monoclonal antibody binding coincided with those conserved among the majority of known enteroviruses, indicating a high diagnostic potential.