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The pseudocalanolides: structure revision of calanolides C and D
T C McKee1, J H Cardellina, G B Dreyer
1Laboratory of Drug Discovery Research and Development, National Cancer Institute, Frederick, Maryland 21702-1201, USA.
Journal of Natural Products
|June 1, 1995
Abstract:
Nmr spectra of synthetic structures corresponding to those initially reported for natural compounds calanolide C [1] and calanolide D [2] showed some subtle differences from those of the natural products. Further analysis has resulted in revision of the structures of the natural compounds, now renamed pseudocalanolides C [3] and D [4]. The absolute stereochemistry of pseudocalanolide C was established as [6S, 7S, 8R] using the modified Mosher's method.