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[The most frequent intrahospital infections in children with malignant diseases]
Insights
Bacterial infections are common in children with cancer, particularly acute leukemias and lymphomas. Prompt treatment of fever associated with infection led to a 96% success rate in managing bacterial infections in pediatric cancer patients.
Area of Science:
- Pediatric Oncology
- Infectious Diseases in Immunocompromised Patients
- Hematology
Context:
- This study examined infection prevalence in 100 pediatric patients with malignant diseases over five years.
- The majority (94%) had acute leukemias or malignant lymphomas.
- Bacterial infections were the most prevalent, accounting for 41% of all infections.
Purpose:
- To investigate the types and prevalence of bacterial, viral, and fungal infections in hospitalized children with cancer.
- To evaluate the clinical presentation and treatment outcomes of infections in this vulnerable population.
Summary:
- Bacterial infections predominated (41%), often presenting with mild clinical symptoms.
- A combined therapeutic approach including chemotherapy, supportive care, and radiotherapy was employed.
- Fever episodes were treated as indicative of infection, guiding therapeutic decisions.
Impact:
- Successful treatment of bacterial infections was achieved in 96% of cases.
- The study highlights the importance of prompt infection management in pediatric cancer patients.
- A low fatality rate (2%) underscores the effectiveness of the treatment strategy.
Abstract:
In 100 children, suffering from different malignant diseases, who were hospitalized on our ward, during the period of 5 years, we have performed the examination of bacterial, viral and fungias infections. The majority of our patients belonged to the group, suffering from acute leukaemias and malignant lymphomas, 94%. In our patients was the clear prevalence of bacterial infections in the 41%, of all our cases. Most of children had the mild clinical picture, as the consequence of infection, while less of them had the middle severe or very severe clinical picture. Our position in treatment, was due to the fact that appearance of every febril epizode is conected with the existence of infection. The therapy was combined, and was consisting from: hemio, haemo, support and Rö therapy, recommended from the Highes group in 1975. The succesful treatment of bacterial infections was in 96%, while in 2%, in spite of therapy the end was fatal.