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[The clinical significance of Serratia infections during the post-operative course (author's transl)]

G C Pugliano, C Asteria, M Zaghis

    L'Ateneo Parmense. Acta Bio-Medica : Organo Della Societa Di Medicina E Scienze Naturali Di Parma
    |January 1, 1978
    PubMed

    Insights

    Serratia infections increasingly occurred in patients receiving antimicrobial therapy, particularly those with urinary catheters. This opportunistic pathogen contributed to mortality in 3 cases, highlighting the need for careful management.

    Area of Science:

    • Clinical microbiology
    • Infectious diseases
    • Hospital epidemiology

    Context:

    • A retrospective analysis of 25 Serratia infection cases between November 1977 and April 1978.
    • Serratia isolates were increasingly identified in urine, surgical incisions, and blood cultures.
    • All patients had prior antimicrobial therapy before Serratia isolation.

    Purpose:

    • To report on the incidence and characteristics of Serratia infections in a clinical setting.
    • To identify risk factors and common sources of Serratia infections.
    • To discuss prophylaxis and antimicrobial treatment strategies for Serratia.

    Summary:

    • Serratia infections were observed in 25 patients, with a high prevalence in urinary tract infections (92%) among those with indwelling urinary catheters.
    • The pathogen was frequently isolated from urine, surgical sites, and blood, often in patients who had received prior antimicrobial treatment.
    • Serratia played a role in the mortality of 3 patients, underscoring its potential as a serious opportunistic pathogen.

    Impact:

    • Highlights the association between indwelling urinary catheters, prior antimicrobial use, and Serratia infections.
    • Emphasizes Serratia's role as an opportunistic pathogen in hospitalized patients.
    • Informs clinical practice regarding surveillance, prophylaxis, and treatment of Serratia infections.

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