Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Bacterial arthritis

D L Goldenberg¹

¹Newton-Wellesley Hospital, Massachusetts, USA.

Current Opinion in Rheumatology

|July 1, 1995

Summary

This summary is machine-generated.

Immune factors, particularly cytokines, drive cartilage destruction in bacterial arthritis. Polymerase chain reaction (PCR) shows promise for diagnosing gonococcal arthritis, especially in culture-negative scenarios.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Further insights in the pain /depression dyad.

International journal of clinical practice·2009

Same author

Circadian rhythms of women with fibromyalgia.

The Journal of clinical endocrinology and metabolism·2001

Same author

The assessment of functional impairment in fibromyalgia (FM): Rasch analyses of 5 functional scales and the development of the FM Health Assessment Questionnaire.

The Journal of rheumatology·2000

Same author

Reduced hypothalamic-pituitary and sympathoadrenal responses to hypoglycemia in women with fibromyalgia syndrome.

The American journal of medicine·1999

Same author

Fibromyalgia syndrome a decade later: what have we learned?

Archives of internal medicine·1999

Same author

Septic arthritis.

Lancet (London, England)·1998

Same journal

New approaches to the management of cutaneous lupus.

Current opinion in rheumatology·2026

Same journal

"Updates in chronic nonbacterial osteomyelitis: emerging insights across the age spectrum".

Current opinion in rheumatology·2026

Same journal

Difficult-to-treat, complex-to-manage, treatment-refractory spondyloarthritis: semantics or substance?

Current opinion in rheumatology·2026

Same journal

Update on IgA nephropathy: implications for treatment in IgA vasculitis: a guide for rheumatologists.

Current opinion in rheumatology·2026

Same journal

Polyarticular juvenile idiopathic arthritis: insights from genetic studies on disease risk and pathogenesis.

Current opinion in rheumatology·2026

Same journal

Immune dysregulation in children with Down syndrome: clinical implications and emerging therapies.

Current opinion in rheumatology·2026

See all related articles

Area of Science:

Immunology
Microbiology
Rheumatology

Background:

Bacterial arthritis involves immune system components, notably cytokines, contributing to cartilage damage.
Gonococcal arthritis, a specific form of bacterial arthritis, presents with distinct clinical features.

Purpose of the Study:

To review the clinical manifestations of gonococcal arthritis.
To evaluate the utility of polymerase chain reaction (PCR) in diagnosing bacterial arthritis, specifically Neisseria gonorrhoeae infections.

Main Methods:

Review of clinical data for gonococcal arthritis.
Application of polymerase chain reaction (PCR) to detect Neisseria gonorrhoeae DNA in synovial fluid samples.

Main Results:

Related Experiment Videos

Experimental models confirm the role of immune factors and cytokines in cartilage destruction during bacterial arthritis.

Detection of Neisseria gonorrhoeae DNA via PCR in synovial fluid was reported in relevant studies.

Conclusions:

Polymerase chain reaction (PCR) may serve as a crucial diagnostic tool for culture-negative bacterial arthritis cases.
PCR application can significantly enhance the understanding of gonococcal arthritis pathophysiology.