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A portable infusion pump, programmable with 16 rates

J Bojsen, K Kølendorf, F Haslev

Biotelemetry and Patient Monitoring

|January 1, 1978

Summary

A new portable infusion pump offers precise drug delivery for long-term therapy. This device effectively managed blood glucose levels in diabetic patients, demonstrating its therapeutic potential.

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Area of Science:

Biomedical Engineering
Medical Devices
Diabetes Management

Background:

Long-term intravenous drug infusion requires reliable and portable delivery systems.
Existing infusion technologies may lack precision or portability for extended therapeutic use.
Effective management of diabetes mellitus necessitates consistent glucose level control.

Purpose of the Study:

To develop and evaluate an external, portable, programmable infusion pump for long-term intravenous drug administration.
To assess the precision and reliability of the developed infusion system.
To investigate the system's efficacy in managing blood glucose levels in diabetic patients.

Main Methods:

Development of an impulse-controlled, portable infusion system comprising a CMOS-electronic unit and an electromechanical infuser with a disposable syringe.
Manual preprogramming of infusion rates ranging from 24 to 384 microliters per 0.5 hour.
Testing the system through continuous intravenous insulin administration in diabetic subjects over 4 days.

Main Results:

The infusion pump demonstrated high precision, with a coefficient of variation of infused volume less than 2% per 0.5 hour.
The system operated continuously for 6-7 days on a single battery charge.
Mean capillary blood glucose concentrations in diabetic subjects were maintained near normal levels (7.0 mmol/L +/- 2.3 SD) during the treatment period.

Conclusions:

The developed portable, programmable infusion pump is a viable tool for precise, long-term intravenous drug delivery.
The system's performance in maintaining near-normal blood glucose levels highlights its potential for diabetes management.
The device offers a reliable and portable solution for therapeutic infusion needs.

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