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Effect of enzymes on the growth of human and animal rotaviruses
1Kyushu Branch Laboratory, National Institute of Animal Health, Kagoshima, Japan.
The Journal of Veterinary Medical Science
|June 1, 1995
Abstract:
The growth of group A human, bovine, equine and porcine rotaviruses were enhanced by pretreatment of virus with pancreatin, trypsin, protease, alkaline phosphatase or pepsin and incorporation of these enzymes in maintenance medium. In contrast, alpha-amylase or lipase inhibited the growth of equine and porcine rotaviruses. The other enzymes, adenosine deaminase, lactase, lysozyme, ribonuclease or triose-phosphate isomerase gave little or no change in the growth of all four rotaviruses.