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Trisomy 14: a recurring cytogenetic abnormality associated with myeloid disorders
H Poirel1, P Jonveaux, M T Daniel
1Unité INSERM U301, Institut de Génétique Moléculaire, Paris, France.
Leukemia & Lymphoma
|May 1, 1995
Abstract:
Trisomy 14 as single karyotype aberration was detected in three patients, two with acute myeloblastic leukemia, AML-M2 type, and one with aplastic anemia. These new observations and the 28 previously reported cases confirm that trisomy 14 is a primary non random change, mostly confined to myeloid disorders.