[Morphology of the development of intraepithelial cervical carcinoma (author's transl)]

By studying histologic preparations of 240 cervices (165 obtained by conization and 75 by hysterectomy), the author tries to answer the following questions: 1. Whick epithelium is responsible for the development of intraepitheilal cervical carcinoma? 2. Does it appear unicentrically or multicentricall? 3. What is the tendency of its spreading? The author concludes that intraepithelial carcinoma of the cervix develops from both kinds of the epithelium, although its development from the squamous epithelium is much rarer, only in 6.2% of cases. It develops muticentrically, by which individual new foci appear in different periods of time. The unicentrical appearance of the carcinoma, confirmed in 45 cases, is not in disagreement with this conclusion. As regards the spreading of intraepithelial carcinoma, the author's observations corroborate those of other authors, i. e. that the carcinoma spreads primarily in the glandular region.