Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Current perspectives in salmonellosis

A J Lax1, P A Barrow, P W Jones

  • 1Institute for Animal Health, Compton, Newbury, Berkshire, UK.

The British Veterinary Journal
|July 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spotlight on avian pathology: Salmonella - new wine and old bottles.

Avian pathology : journal of the W.V.P.A·2021
Same author

Deciphering the role of <i>ttrA</i> and <i>pduA</i> genes for <i>Salmonella enterica</i> serovars in a chicken infection model.

Avian pathology : journal of the W.V.P.A·2021
Same author

Combination of competitive exclusion and immunisation with a live Salmonella vaccine in newly hatched chickens: Immunological and microbiological effects.

Research in veterinary science·2016
Same author

Experimental infection of chickens by a flagellated motile strain of Salmonella enterica serovar Gallinarum biovar Gallinarum.

Veterinary journal (London, England : 1997)·2016
Same author

The contribution of genes required for anaerobic respiration to the virulence of Salmonella enterica serovar Gallinarum for chickens.

Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]·2013
Same author

New viral pathogens from wildlife.

Bulletin et memoires de l'Academie royale de medecine de Belgique·2012
Same journal

Incidence of pathogenic bacteria in market milk of Cairo.

The British veterinary journal·2010
Same journal

A case of multiple arthritis in a thoroughbred.

The British veterinary journal·2010
Same journal

Chemotherapy of Erysipelothrix rhusiopathiae infections in mice.

The British veterinary journal·2010
Same journal

Critical anthelmintic tests in cattle.

The British veterinary journal·2010
Same journal

A simple technique for the fixation and staining of Trichomonas in cultures and vaginal mucus.

The British veterinary journal·2010
Same journal

Effect of feeding green food to the pregnant sow on the incidence of piglet anaemia.

The British veterinary journal·2010
See all related articles

Salmonellosis pathogenesis is complex, with many virulence factors and host adaptation mechanisms still poorly understood. Ongoing research uses molecular techniques and new vaccine designs to combat this global health issue.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Bacterial Pathogenesis

Background:

  • Salmonellosis is a significant global health concern affecting both humans and animals.
  • Despite extensive research, key aspects of Salmonella pathogenesis remain unclear, including host adaptation and virulence factor function.

Purpose of the Study:

  • To elucidate the complex pathogenesis of Salmonella infections.
  • To identify and characterize virulence genes and regulatory systems involved in Salmonella disease.
  • To explore novel vaccine strategies and diagnostic approaches for salmonellosis.

Main Methods:

  • Utilizing molecular techniques and in vitro model systems to identify genes involved in adhesion, invasion, and toxin production.
  • Defining essential genes on virulence plasmids necessary for systemic infection.

Related Experiment Videos

  • Investigating gene systems regulating bacterial virulence.

    • Main Results:

    • Several genes implicated in adhesion, invasion, and potential toxin production have been identified, though their precise roles require further definition.
    • Essential genes on virulence plasmids, including regulatory elements, are crucial for systemic infection establishment.
    • Gene systems involved in the regulation of virulence have been a focus of recent research.

    Conclusions:

    • A comprehensive understanding of Salmonella pathogenesis is still evolving, with many molecular mechanisms yet to be fully elucidated.
    • New vaccine candidates based on rational attenuation and heterologous antigens are under development and clinical trials.
    • Advances in understanding salmonellosis pathogenesis may offer insights applicable to other bacterial infections and improve diagnostic capabilities using techniques like PCR.