[Pathologic findings in the uterine cervix--diagnostic aspects]

Area of Science:

• Gynecologic Pathology
• Oncology
• Infectious Diseases

Context:

• Routine bioptic diagnoses of cervical lesions were analyzed over a five-year period.
• The study examined 651 cervical lesions, representing 26% of all registered neoplastic and precancerous lesions of the female genital (2513 cases).
• Precancerous lesions of the exocervix and endocervix predominated (68%), followed by malignant tumors (28%).

Purpose:

• To present the findings of routine bioptic diagnoses for cervical lesions.
• To investigate the prevalence of precancerous and malignant changes in the cervix uteri.
• To explore the correlation between Human Papillomavirus (HPV) infection and cervical pathologies.

Summary:

• Bioptic diagnoses revealed 651 cervical lesions, with a high prevalence of precancerous conditions (68%) and a significant proportion of malignant tumors (28%).
• A two-year cytological evaluation of 27,093 patients identified HPV infection in 2.8% (748 cases).
• Histologic correlation confirmed HPV infection in 124 out of 467 patients with dysplastic or malignant exocervical lesions.

Impact:

• Highlights the significant role of HPV infection in the development of cervical pathologies, aligning with global trends.
• Provides crucial data on the distribution of precancerous and malignant lesions of the cervix uteri.
• Underscores the importance of integrating cytological and bioptic examinations for accurate diagnosis and management of cervical conditions.