Related Experiment Video
Updated: Aug 6, 2026
Automated 3D Optical Coherence Tomography to Elucidate Biofilm Morphogenesis Over Large Spatial Scales
Published on: August 21, 2019
Three-dimensional digital subtraction modeling of corneal topography
1Cornea Service, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA.
Background:
The introduction of a system of classification of color-coded computerized topography has proved of great clinical value but may be misinterpreted by some who assume that the color plots represent actual corneal contour.
Methods:
A three-dimensional system of contour modeling is used to plot equivalents of each category of corneal shape. The round, oval, symmetric bowtie, and asymmetric bowtie of the widely used classification schema are each translated into contour equivalents. Digital subtraction of an appropriate sphere from the contour data is central to the transformation.
Results:
While round- and oval-type color-coded refractive power plots translate into fairly intuitive contour images, symmetric and asymmetric bowties produce surprising results. We demonstrated that the bowtie appearance is a result of the changing curvatures present between the two principal meridia of the toroidal surface.
Conclusion:
The shape characteristics of the corneal surface dictate the familiar color-coded dioptric plots.
