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Peroxisomal beta-oxidation of fatty acids in bovine and rat liver
D E Grum1, L R Hansen, J K Drackley
1Department of Animal Sciences, University of Illinois, Urbana 61801, USA.
Abstract:
Hepatic peroxisomal beta-oxidation rates were compared in liver homogenates from cows and rats during different nutritional and physiological states. Peroxisomal oxidation in liver homogenates from cows represented 50% and 77% of the total capacity for the initial cycle of beta-oxidation of palmitate and octanoate, respectively, but only 26% and 65% for rats. Lactation or food deprivation did not alter rates of hepatic peroxisomal beta-oxidation of palmitate or octanoate in cows. Fasting and clofibrate treatment increased rates of total and peroxisomal beta-oxidation of palmitate and octanoate in rat liver.