Related Experiment Video
Updated: Sep 16, 2026
Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder
Published on: April 26, 2024
Self-reported depressive symptoms in association with medication exposures among medical inpatients: a
S B Patten1, J V Williams, E J Love
1Department of Psychiatry, Faculty of Medicine, University of Calgary, Alberta.
Objective:
To evaluate associations between exposure to three classes of medications (angiotensin converting enzyme inhibitors, calcium channel blockers, and corticosteroids) and self-reported depressive symptoms.
Method:
The study utilised a cross-sectional study design in a sample of medical inpatients.
Results:
Associations between self-reported depressive symptoms and exposure to angiotensin converting enzyme inhibitors or calcium channel blockers were not observed. However, an association between self-reported depressive symptoms and corticosteroid exposure was identified. The association was strongest in subjects reporting a past history of depression or a family history of depression. The strength of the corticosteroid-depressive symptom association was comparable with that of associations observed for age, poverty and psychosocial stress.
Conclusions:
Depressive symptoms among medical inpatients have a biopsychosocial etiology. Corticosteroid exposure may be a biological risk factor for depressive symptoms in this population.
