[Evaluation of prognostic factors in malignant synovioma]

Prognostic factors in 78 patients (36 males and 42 females) aged 9 to 68 treated for malignant synovioma in Warsaw Institute of Oncology between 1950 and 1988 have been assessed. Case history ranged from 1 month to 18 years. The neoplasm was found primarily within lower limb- 45 cases (58%), upper limb- 23 (29%), head, neck and trunk were the sites in 10 patients (13%). In 37 cases tumor diameter was less then 5 cm (T1) and in 37 more (T2 and T3). The diameter remained unknown in 4 patients. Monophase structure was found in 50 cases, biphase structure in 28. Five years survival constituted 48%, 10 years- 28%. The best prognostic value had size of the tumor and the duration of the symptoms. The size below 5 cm gave 58% years survival, above 5 cm only 34%. The history longer then 12 months offered 70% of 5 years survival and shorter one only 27%. Patients with longer history and smaller size of the tumor had significantly better prognosis then those with short history and tumor exceeding 5 cm in size. Females with tumor larger than 5 cm had much better changes then males. Remote metastases worsened the prognosis markedly. The age, localization and histological type of the neoplasm had no prognostic value.