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Invasive fungal sinusitis in the immunocompromised pediatric patient
B K Lansford1, C M Bower, R W Seibert
1Arkansas Children's Hospital, Little Rock 72202-3591, USA.
Ear, Nose, & Throat Journal
|August 1, 1995
Summary
Invasive fungal sinusitis is rare in children but increasing due to immune-suppressing treatments. Early diagnosis and a multi-pronged treatment approach are crucial for survival.
Area of Science:
- Pediatric Otolaryngology
- Infectious Diseases
- Mycology
Background:
- Invasive fungal sinusitis (IFS) is an uncommon but serious condition in pediatric patients.
- Its incidence is rising, potentially linked to increased use of immunosuppressive therapies like antibiotics, steroids, and chemotherapy.
Observation:
- Presents three pediatric cases of IFS, detailing symptoms, diagnostic imaging (CT), surgical, and histopathological findings.
- Highlights the importance of early clinical suspicion and comprehensive diagnostic evaluation.
Findings:
- Successful treatment requires a multidisciplinary approach including managing underlying conditions, surgical intervention, and systemic antifungal medication.
- Histopathological confirmation is essential for diagnosis.
Implications:
- Prompt diagnosis and integrated treatment strategies involving otolaryngologists, pediatricians, and pathologists are vital for improving patient outcomes.
- Restoration of immune function is a critical factor for survival in pediatric IFS.