Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

An experimental study of optimal parameters for bipolar electrocoagulation

A V Dilley1, M A Friend, D L Morris

  • 1School of Surgery, University of New South Wales, St. George Hospital, Kogarah, Sydney, NSW, Australia.

Gastrointestinal Endoscopy
|July 1, 1995
PubMed
Summary

Optimal BICAP therapy for bleeding peptic ulcers involves high probe force and long coagulation times. Low generator output is recommended for effective arterial welding in vitro.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Oxaliplatin versus Mitomycin C for HIPEC in colorectal cancer peritoneal carcinomatosis.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2016
Same author

Preliminary Evidence for Effectiveness of Resourcefulness Training in Women Dementia Caregivers.

Journal of family medicine·2016
Same author

Is mucin a determinant of peritoneal dissemination of gastrointestinal cancer? Analysis of mucin depletion in two preclinical models.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·2016
Same author

Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Methodology, Drugs and Bidirectional Chemotherapy.

Indian journal of surgical oncology·2016
Same author

High risk features of primary colorectal carcinomas which subsequently undergo peritonectomy.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2016
Same author

Laparoscopic hyperthermic intraperitoneal chemotherapy (HIPEC) for refractory malignant ascites in patients unsuitable for cytoreductive surgery.

International journal of surgery (London, England)·2015

Area of Science:

  • Vascular Surgery
  • Gastroenterology
  • Biomedical Engineering

Background:

  • Bleeding peptic ulcers are a significant cause of morbidity and mortality.
  • BICAP therapy is an endoscopic hemostasis method used to control gastrointestinal bleeding.
  • Optimizing BICAP therapy parameters is crucial for achieving effective hemostasis.

Purpose of the Study:

  • To investigate the impact of various parameters on the quality of arterial welds created by BICAP therapy.
  • To determine the optimal settings for BICAP therapy in achieving strong and reliable arterial welds.
  • To provide evidence-based recommendations for BICAP therapy in treating bleeding peptic ulcers.

Main Methods:

  • In vitro study using rabbit arteries (3-5 mm hemicircumference).

Related Experiment Videos

  • Variable application of probe force (94, 250, 491 g), coagulation time (2, 10, 20 secs), and generator output (5, 10).
  • Assessment of arterial weld strength through testing to destruction via increasing intraluminal pressure.
  • Main Results:

    • The strongest arterial welds were achieved with the highest probe force and longest coagulation time (20 seconds).
    • Increased BICAP generator output (10 vs. 5) did not significantly improve weld strength.
    • Optimal conditions involved high force and extended coagulation, irrespective of generator output.

    Conclusions:

    • BICAP therapy for bleeding peptic ulcers should utilize maximal compression force and a minimum coagulation time of 20 seconds.
    • A low BICAP generator output (≤5) is recommended for effective hemostasis.
    • These findings support optimizing BICAP settings for improved clinical outcomes in managing gastrointestinal hemorrhage.