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Solid-phase synthesis of peptide haptens containing a cysteine-sulfur mustard adduct
D Noort1, E H Jacobs, A Fidder
1Department of Chemical Toxicology, TNO Prins Maurits Laboratory, Rijswijk, The Netherlands.
Abstract:
Solid-phase synthesis of peptide haptens containing 2-[2-(S-cysteinyl)ethanol has been achieved by solution-phase synthesis of a properly protected S-alkylated cysteine derivative and subsequent solid-phase incorporation.