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Related Experiment Videos

Ocular globe topography in radiotherapy

U Karlsson1, T Kirby, W Orrison

  • 1Department of Radiation Oncology, East Carolina University, Greenville, NC, USA.

International Journal of Radiation Oncology, Biology, Physics
|October 15, 1995
PubMed
Summary
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Eyelid markers offer more precise localization of the ocular lens and retina than the lateral canthus during radiotherapy. This improves individualized ocular globe shielding and informs decisions about lens shielding when the olfactory bulb requires irradiation.

Area of Science:

  • Radiotherapy Physics
  • Ophthalmology
  • Medical Imaging

Background:

  • Accurate localization of ocular structures (lens, retina) is crucial in radiotherapy to minimize radiation dose to healthy tissues.
  • Current methods for localizing these soft tissues are often imprecise, posing challenges for effective treatment planning.
  • The olfactory bulb is also a critical structure to consider for radiation exposure during lateral beam treatments.

Purpose of the Study:

  • To evaluate the accuracy of eyelid markers versus the lateral canthus as reference points for localizing the ocular lens and retina in lateral beam radiotherapy simulations.
  • To determine the constancy of anatomical relationships between eyelid markers and ocular structures.
  • To provide data for improving individualized ocular globe and lens shielding strategies.

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Main Methods:

  • Analysis of 66 pre-Magnetic Resonance Image (MRI) normal orbital computed tomography (CT) scans from adult patients.
  • Measurement of sagittal distances from eyelid and lateral canthus to the posterior lens surface and globe's posterior pole.
  • Assessment of supero-inferior distances between the lens and cribriform plate in lateral projections.

Main Results:

  • Eyelid topography demonstrated greater individual constancy to the lens and retina compared to the lateral canthus.
  • Minimal supero-inferior separation was observed between the lens and the cribriform plate in lateral projections.
  • The lateral canthus proved unreliable for specifying precise lens or retina locations.

Conclusions:

  • Eyelid markers provide more accurate anatomical information for radiotherapy planning than the lateral canthus.
  • Individualized ocular globe shielding is necessary based on accurate soft tissue localization.
  • Lens shielding requires careful consideration when lateral beams are used for olfactory bulb irradiation.