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Allergic rhinitis in a herd of cattle
T W Olchowy1, L J Gershwin, D F Dean
1Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville 37901, USA.
Journal of the American Veterinary Medical Association
|November 1, 1995
Summary
Allergic rhinitis in Hereford cattle presents with nasal discharge and lesions. An exaggerated immune response to environmental allergens, potentially blocked by IgG, causes these symptoms.
Area of Science:
- Veterinary Medicine
- Immunology
- Animal Science
Background:
- Allergic rhinitis is a common condition affecting various species.
- Understanding the immunological basis of allergic rhinitis in cattle is crucial for herd health management.
Observation:
- Hereford cattle exhibited clinical signs of rhinitis, including nasal discharge and irritation.
- Nasal passages showed proliferative lesions, with eosinophils predominant in discharge.
- Histopathology confirmed chronic proliferative eosinophilic rhinitis.
Findings:
- Complete blood counts (CBC) and plasma fibrinogen were within normal limits.
- Intradermal allergen testing and ELISA indicated an exaggerated IgE-mediated response to environmental allergens.
- Allergen-specific IgG antibodies may have provided a blocking effect, mitigating clinical signs in some animals.
Implications:
- This study highlights the role of environmental allergens in bovine allergic rhinitis.
- The findings suggest a potential mechanism involving IgE and IgG in disease presentation.
- Further research can inform diagnostic and therapeutic strategies for allergic respiratory conditions in cattle.