Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Computational method for determination of bone and joint loads using bone density distributions

K J Fischer1, C R Jacobs, D R Carter

  • 1Rehabilitation Research and Development Center, Department of Veterans Affairs Medical Center, Palo Alto, CA 94304-1200, USA.

Journal of Biomechanics
|September 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Fungal Planet description sheets: 1550-1613.

Persoonia·2024
Same author

Effects of a CO<sub>2</sub>-enriched atmosphere on the growth and competitive interaction of a C<sub>3</sub> and a C<sub>4</sub> grass.

Oecologia·2017
Same author

Lengthening primary cilia enhances cellular mechanosensitivity.

European cells & materials·2017
Same author

The analysis of photosynthetic performance in leaves under field conditions: A case study using Bruguiera mangroves.

Photosynthesis research·2014
Same author

Dynamics of the primary cilium in shear flow.

Biophysical journal·2012
Same author

Primary cilia act as mechanosensors during bone healing around an implant.

Medical engineering & physics·2012

This study introduces a novel method to determine bone loading history by analyzing bone density distribution. This technique accurately estimates past mechanical stresses, aiding in understanding bone adaptation in living and extinct animals.

Area of Science:

  • Biomechanics
  • Paleontology
  • Bone Physiology

Background:

  • Bone structure is shaped by mechanical forces during development.
  • Bone geometry and density reflect an individual's loading history.
  • Understanding bone loading is crucial for diagnosing conditions and reconstructing past environments.

Purpose of the Study:

  • To develop and validate a method for determining bone loading conditions.
  • To utilize bone density distribution as a proxy for mechanical loading history.
  • To assess the potential of this method for analyzing extant and extinct species.

Main Methods:

  • Applied a mathematical theory linking stress history to bone remodeling.
  • Developed an optimization procedure to determine dominant bone loading.

Related Experiment Videos

  • Used a 2D finite element model with a standard bone density distribution.
  • Adjusted basic load magnitudes to match simulated stress stimuli.

    • Main Results:

    • The density-based method accurately determined original loads in test cases.
    • The optimization procedure successfully identified load magnitudes and locations.
    • The method demonstrated effectiveness in a simplified bone model.

    Conclusions:

    • The developed method shows promise for estimating in vivo bone loads.
    • This technique can be applied to both living and fossilized animals.
    • Bone density analysis offers a powerful tool for biomechanical reconstruction.