Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The effect of triclosan on developing gingivitis

P Ramberg1, Y Furuichi, D Sherl

  • 1Department of Periodontology, Faculty of Odontology, Göteborg University, Sweden.

Journal of Clinical Periodontology
|June 1, 1995
PubMed
Summary

This study investigated triclosan mouthrinse effects on gingivitis. While triclosan with tween 80 showed higher plaque buildup, both triclosan formulations did not significantly differ in preventing gingival inflammation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Glioblastoma stem cells: a new target for metformin and arsenic trioxide.

Journal of biological regulators and homeostatic agents·2014
Same author

Android and ODK based data collection framework to aid in epidemiological analysis.

Online journal of public health informatics·2014
Same author

A two-year clinical study comparing the effect of dentifrices on selected dental materials.

Journal of oral rehabilitation·2012
Same author

Metformin plus temozolomide-based chemotherapy as adjuvant treatment for WHO grade III and IV malignant gliomas.

Journal of B.U.ON. : official journal of the Balkan Union of Oncology·2012
Same author

Zinc opposes genotoxicity of cadmium and vanadium but not of lead.

Journal of biological regulators and homeostatic agents·2012
Same author

Mithridates VI Eupator of Pontus and mithridatism.

Allergy·2011

Area of Science:

  • Oral Health
  • Periodontology
  • Antimicrobial Agents

Background:

  • Gingival inflammation is a common oral health issue.
  • Triclosan is an antimicrobial agent used in oral hygiene products.
  • Understanding triclosan's efficacy in preventing gingivitis is crucial.

Purpose of the Study:

  • To evaluate the effect of triclosan mouthrinse on developing gingival inflammation.
  • To compare the efficacy of two triclosan formulations with different surfactants.

Main Methods:

  • A 2-week, double-blind, cross-over experimental gingivitis study.
  • 10 volunteers with healthy gingiva refrained from mechanical oral hygiene.
  • Participants rinsed twice daily with either 0.06% triclosan + 2% tween 80 or 0.06% triclosan + 0.25% sodium lauryl sulphate.

Related Experiment Videos

Main Results:

  • Significantly less plaque accumulation was observed with the triclosan + sodium lauryl sulphate formulation compared to triclosan + tween 80.
  • Both triclosan formulations led to comparable increases in gingivitis scores over 14 days.
  • No statistically significant differences in gingivitis development were found between the two experimental periods.

Conclusions:

  • While triclosan formulations may impact plaque levels differently, they demonstrated similar efficacy in preventing experimental gingival inflammation in this study.
  • Further research may be needed to fully elucidate the role of surfactants in triclosan mouthrinses.
  • Triclosan's anti-inflammatory effect on gingivitis appears consistent across tested formulations under these experimental conditions.