Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Periodontal tissue-vitality after different etching modalities

J Blomlöf1, S Lindskog

  • 1Department of Oral Histology and Cell Biology, School of Dentistry, Karolinska Institutet, Stockholm, Sweden.

Journal of Clinical Periodontology
|June 1, 1995
PubMed
Summary

Low pH etching agents like phosphoric and citric acids cause immediate tissue damage to periodontal tissues. Neutral pH agents, such as EDTA, do not show these necrotizing effects, suggesting potential benefits for healing.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Gastrin-releasing peptide receptor expression in gastrointestinal stromal tumours.

ESMO gastrointestinal oncology·2026
Same author

Image of an adrenal mesenchymoma.

ANZ journal of surgery·2023
Same author

Relative blood loss and operative time can predict length of stay following orthognathic surgery.

International journal of oral and maxillofacial surgery·2016
Same author

Factors influencing intraoperative blood loss in orthognathic surgery.

International journal of oral and maxillofacial surgery·2016
Same author

Analgesic efficacy with rapidly absorbed ibuprofen sodium dihydrate in postsurgical dental pain: results from the randomized QUIKK trial.

International journal of clinical pharmacology and therapeutics·2011
Same author

Histological findings in soft tissues around temporomandibular joint prostheses after up to eight years of function.

International journal of oral and maxillofacial surgery·2010

Area of Science:

  • Periodontal tissue response to chemical agents
  • Dental material science and biocompatibility

Background:

  • Etching agents are used in dentistry to prepare tooth surfaces.
  • Understanding the immediate effects of these agents on periodontal tissues is crucial for clinical application.

Purpose of the Study:

  • To investigate the immediate necrotizing effects of low and neutral pH etching agents on periodontal tissues.
  • To compare the tissue response to phosphoric acid, citric acid, and EDTA.

Main Methods:

  • Periodontal tissues and mucosal flaps were exposed to low pH (phosphoric, citric acids) and neutral pH (EDTA) etching agents.
  • Necrotizing effects and penetration depth were observed within short time frames (20 seconds to 3 minutes).

Main Results:

Related Experiment Videos

  • Low pH agents (phosphoric and citric acids) induced immediate necrosis within 20 seconds.
  • Necrosis penetration depth increased over time for low pH agents.
  • EDTA, a neutral pH agent, did not cause detectable necrosis during the experimental period.

Conclusions:

  • Low pH etching agents can cause immediate necrotizing effects on periodontal tissues.
  • Neutral pH agents like EDTA appear to be less cytotoxic in the short term.
  • Further in vivo and clinical studies are needed to evaluate long-term healing and compare the clinical preference for neutral pH etching.