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Updated: Aug 7, 2026

Multifocal Electroretinograms
Published on: December 4, 2011
[Macular complications of synthetic antimalarials. Apropos of a case]
F Ducousso1, J C Ballion, J L Kovalski
1Service d'Ophtalmologie, Hôpital d'Instruction des Armées Robert Picqué, Bordeaux-Armées
Abstract:
The clinico-pathological findings in a 17-year-old girl with an "oeil de boeuf" maculopathy are reported together with the aetiological elements involved (hereditary or toxic maculopathy). The case was a second stage typical maculopathy due to antimalarial drugs. These patients were particularly susceptible, probably because of impaired renal function, since the total dose absorbed (140 g. chloroquine) was low. Ophthalmologic monitoring is required to prevent intoxication. Clinical examination, angiography and automatic perimetry and contrast sensitivity test are needed to detect the first effect of toxicity.
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