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Updated: Jul 16, 2026
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Fluorescence-microscopy Screening and Next-generation Sequencing: Useful Tools for the Identification of Genes Involved in Organelle Integrity
Published on: April 13, 2012
Mapping information roadways from sequence to phenotype and across species
1Department of Biology, Yale University, New Haven, CT 06520-8104, USA.
The Journal of Heredity
|September 1, 1995
Summary
This study explores computerizing genetic information and linking it with molecular biology databases. It highlights the importance of interconnected organismal and molecular data for research advancements.
Area of Science:
- Bioinformatics
- Computational Biology
- Genomics
Background:
- Effective management of complex genetic data is crucial for modern biological research.
- Integrating diverse biological databases presents significant challenges.
- The need for standardized methods to represent and connect genetic information is growing.
Purpose of the Study:
- To discuss methods for computerizing detailed genetic information.
- To explore connectivity between organismal and molecular biology databases.
- To address challenges in developing and maintaining accessible genetic databases.
Main Methods:
- Illustrating interconnections using examples from E. coli and maize databases.
- Demonstrating connections with public resources like GenBank and SwissProt.
- Discussing strategies for database development and maintenance.
Main Results:
- Established pathways for linking organismal and molecular data via the World Wide Web.
- Showcased successful integration examples using specific model organisms.
- Identified key issues in the development and public accessibility of genetic databases.
Conclusions:
- Computerization and interconnectedness of genetic information are vital for biological research.
- Web-based integration of databases like GenBank and SwissProt facilitates data access.
- Addressing development, maintenance, and usability is key for widespread adoption of genetic information systems.
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