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Variability in the growth sustaining capacity of medium batches
A W Hügin1, E Rudikoff, H C Morse
1Laboratory of Immunopathology, NIAID, National Institute of Health, Bethesday, MD 20892, USA.
Journal of Immunological Methods
|October 12, 1995
Abstract:
Medium batches, analysed in various spontaneous and mitogen induced proliferation assays, revealed heterogeneity in their growth promoting activity. This can critically affect test results and suggests that culture media can be a source of variability and problems in cell culture work. The manufacturers of media should broaden their quality control of medium batches.