Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Laryngeal squamous cell carcinoma with sebaceous differentiation

J G Panayiotides1, P Arapantoni-Dadioti, C G Banis

  • 1Department of Histopathology, Metaxas Memorial Cancer Hospital, Piraeus, Greece.

The Journal of Laryngology and Otology
|August 1, 1995
PubMed
Summary

This case report details a rare supraglottic laryngeal squamous cell carcinoma with sebaceous differentiation. Despite treatment, the patient experienced aggressive metastasis and succumbed to the disease seven months post-surgery.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nasopharyngeal angiofibroma in an adult with Proteus syndrome. First reported case.

Hippokratia·2018
Same author

Discordant expression of hormone receptors and HER2 in breast cancer. A retrospective comparison of primary tumors with paired metachronous recurrences or metastases.

Journal of B.U.ON. : official journal of the Balkan Union of Oncology·2012
Same author

Identification and validation of gene expression models that predict clinical outcome in patients with early-stage laryngeal cancer.

Annals of oncology : official journal of the European Society for Medical Oncology·2012
Same author

Vulvar merkel carcinoma: a case report.

Case reports in medicine·2011
Same author

Different HLA-DR expression in endometriotic and adenomyotic lesions: correlation with transvaginal ultrasonography findings.

Archives of gynecology and obstetrics·2009
Same author

Analysis of 7 immunohistochemical markers in male germ cell tumors demonstrates the prognostic significance of p53 and MIB-1.

Anticancer research·2009

Area of Science:

  • Oncology
  • Pathology
  • Laryngology

Background:

  • Squamous cell carcinoma is the most common laryngeal cancer.
  • Sebaceous differentiation in laryngeal squamous cell carcinoma is exceptionally rare.
  • This report presents the second documented case of this specific subtype.

Observation:

  • A 68-year-old male presented with supraglottic laryngeal squamous cell carcinoma.
  • A right cervical lymph node metastasis showed only squamous cell components.
  • The patient received intensive post-operative chemotherapy.

Findings:

  • The patient developed distant metastases in the left cervical area and left pulmonary hilus.
  • The disease proved rapidly fatal, with death occurring seven months post-operatively.

Related Experiment Videos

  • Histopathological analysis of the lymph node metastasis revealed exclusively squamous cells, lacking sebaceous differentiation.

    • Implications:

    • This case highlights the aggressive potential of laryngeal squamous cell carcinoma with sebaceous differentiation.
    • Further research is needed to understand the biological behavior and optimal treatment strategies for this rare variant.
    • Increased awareness among clinicians and pathologists is crucial for accurate diagnosis and management.