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Medulloblastoma in adults
1Department of Neurosciences, King Faisal Specialist Hospital and Research Centre, Riyad, Arabia Saudita.
Journal of Neurosurgical Sciences
|December 1, 1994
Summary
This study reviewed 17 adult medulloblastoma cases managed between 1981-1992. Adult medulloblastoma patients often present with hydrocephalus and undergo surgical tumor removal followed by radiation therapy.
Area of Science:
- Neuro-oncology
- Adult brain tumors
- Medulloblastoma epidemiology
Background:
- Medulloblastoma is a primary brain tumor typically diagnosed in children.
- Adult medulloblastoma is rare, necessitating specific clinical and management insights.
Observation:
- Seventeen adult patients (≥16 years) with medulloblastoma were analyzed.
- Tumor locations included midline (9) and hemispheres (8); desmoplastic variant was common (9 patients).
- Hydrocephalus occurred in 14 patients, with 7 requiring shunting.
Findings:
- All patients underwent subtotal or gross total tumor removal.
- Sixteen patients received postoperative radiation therapy; one refused.
- Two patients received chemotherapy for recurrent disease.
Implications:
- Adult medulloblastoma management involves surgery and radiation, with chemotherapy reserved for recurrence.
- Understanding adult medulloblastoma presentation and treatment is crucial for neuro-oncologists.
- Further research into adult medulloblastoma outcomes and novel therapies is warranted.