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Sepsis during pregnancy
1St. John's Mercy Medical Center, USA.
The incidence of maternal mortality related to sepsis has decreased during the past 2 decades because of the availability of broad spectrum antibiotics and advances in critical care. However, sepsis continues to account for approximately 7.6% of maternal deaths in the United States. This article focuses on intraamniotic infection as a source of maternal sepsis. Common causative pathogens, typical sources of sepsis, and related pathophysiology are reviewed. Nursing and medical management strategies are included. A case study is presented to illustrate the typical clinical course from infection, to bacteremia, sepsis, and septic shock.
The incidence of maternal mortality related to sepsis has decreased during the past 2 decades because of the availability of broad spectrum antibiotics and advances in critical care. However, sepsis continues to account for approximately 7.6% of maternal deaths in the United States. This article focuses on intraamniotic infection as a source of maternal sepsis. Common causative pathogens, typical sources of sepsis, and related pathophysiology are reviewed. Nursing and medical management strategies are included. A case study is presented to illustrate the typical clinical course from infection, to bacteremia, sepsis, and septic shock.