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Responders and nonresponders to transurethral microwave thermotherapy: a multicenter retrospective analysis
M J de Wildt1, A Tubaro, K Höfner
1Department of Urology, Nijmegen University Hospital, The Netherlands.
Purpose:
We attempted to identify any parameter that could possibly lead to a successful treatment outcome after transurethral microwave thermotherapy.
Materials And Methods:
Clinical parameters and treatment profiles of 292 patients were analyzed in a retrospective multicenter manner. Responder and nonresponder groups were identified according to a given definition.
Results:
No statistically significant differences in baseline characteristics were found. Responders showed a 76% symptomatic improvement rate compared to 27% in nonresponders, and an 82% improvement rate in peak flow compared to a 5% decrease in nonresponders. Responders also showed a significantly greater increase in posttreatment PSA level and a significantly greater amount of energy released during treatment.
Conclusions:
No baseline clinical parameter is capable of predicting treatment outcome.