Moyamoya disease in Malaysia: two documented cases

Area of Science:

• Neurology
• Vascular Neurology
• Radiology

Background:

• Moyamoya disease is a rare, progressive cerebrovascular disorder.
• It is characterized by stenosis of the terminal portion of the internal carotid arteries and the proximal portions of the anterior and middle cerebral arteries.
• The condition often leads to ischemic or hemorrhagic strokes, particularly in young adults.

Observation:

• This report presents two cases of moyamoya disease diagnosed in Malaysia.
• The patients' clinical presentations and diagnostic imaging findings are detailed.
• Cerebral angiography was the definitive diagnostic tool used in both cases.

Findings:

• The two cases illustrate the occurrence of moyamoya disease in the Malaysian population.
• Diagnostic cerebral angiography confirmed the characteristic vascular changes of moyamoya disease.
• The findings highlight the importance of considering moyamoya disease in young stroke patients.

Implications:

• Early diagnosis and appropriate management of moyamoya disease are crucial for preventing recurrent strokes.
• Increased awareness of moyamoya disease among clinicians in Malaysia may improve diagnostic rates.
• Further research into the prevalence and specific characteristics of moyamoya disease in Malaysia is warranted.