Acute renal failure in high dose carboplatin chemotherapy
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J Frenkel1, G Kool, J de Kraker
1Department of Paediatrics, Emma Kinderziekenhuis/Academic Medical Centre, University of Amsterdam, The Netherlands.
Medical and Pediatric Oncology
|December 1, 1995
Abstract:
Carboplatin has been reported to cause acute renal failure when administered in high doses to adult patients. We report a 4 1/2-year-old girl who was treated with high-dose carboplatin for metastatic parameningeal embryonal rhabdomyosarcoma. Acute renal failure developed followed by a slow partial recovery of renal function. Possible contributing factors are discussed.