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[Scintigraphy of the parathyroid glands with 99mTc-MIBI]
F Grünwald1, G Späth, C Menzel
1Klinik und Poliklinik für Nuklearmedizin, Universität Bonn.
Aim:
Since about 3 years 99mTc-MIBI is used instead of 201Tl/99mTc subtraction scintigraphy for the localization of parathyroid involvement in hyperparathyroidism (HPT). The sensitivity of the new method was evaluated.
Patients And Methods:
24 patients aged between 28 and 83 years with surgically confirmed primary HPT were studied. Planar images were acquired 15 minutes and 3 hours after tracer injection. Additionally, in 9 patients dynamic images were obtained for 2 hours to study tracer kinetics.
Results:
19 out of 24 adenomas (79%) were identified correctly with 99mTc-MIBI.
Conclusion:
The sensitivity of the scintigraphy using 99mTc-MIBI is in the range of the 201Tl/99mTc subtraction scintigraphy. Because of the superior logistic and the lower radiation exposure, 99mTc-MIBI can replace the 201Tl/99mTc scintigraphy in the preoperative diagnostic assessment.