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Related Experiment Videos

Calcium, why and how much?

G M Palmieri1

  • 1Memphis Metabolic Bone Center, Department of Medicine, University of Tennessee, USA.

Mineral and Electrolyte Metabolism
|January 1, 1995
PubMed
Summary
This summary is machine-generated.

Higher calcium intake may prevent various diseases by suppressing parathyroid hormone, a key factor in modern illnesses and aging. This suggests increasing dietary calcium is crucial for preventive medicine.

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Area of Science:

  • Biochemistry
  • Preventive Medicine
  • Cell Biology

Background:

  • Calcium (Ca) is essential for preventing osteoporosis.
  • Its role in preventing unrelated diseases like hypertension, colon cancer, and kidney stones is unclear.
  • Maintaining a low cytosolic Ca concentration is vital for cell health.

Purpose of the Study:

  • To explore a unified hypothesis for calcium's diverse health benefits.
  • To investigate the role of parathyroid hormone (PTH) in calcium's effects.
  • To assess the impact of modern vs. preneolithic calcium intake levels.

Main Methods:

  • Review of existing literature on calcium's physiological effects.
  • Analysis of the relationship between calcium, parathyroid hormone, and disease.

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  • Consideration of anthropologic data on historical dietary calcium intake.

    • Main Results:

    • A proposed hypothesis links calcium's benefits to the suppression of parathyroid hormone (PTH) secretion.
    • Suppressed PTH may mitigate conditions such as hypertension and cardiomyopathy.
    • Anthropologic data suggests significantly higher preneolithic calcium intake (approx. 1,600 mg/day).

    Conclusions:

    • Elevated PTH levels in genetically susceptible individuals may worsen modern diseases and aging.
    • Increased dietary calcium intake could be a significant goal for preventive medicine.
    • Higher calcium intake is recommended for both sexes to promote health.