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Cryptococcal prostatitis in a patient with Behçet's disease treated with fluconazole
H Fuse1, M Ohkawa, K Yamaguchi
1Department of Urology, Houju Memorial Hospital, Ishikawa, Japan.
Mycopathologia
|June 1, 1995
Summary
A prostate infection caused by Cryptococcus neoformans in a patient with Behçet's disease led to acute urinary retention. This localized infection was effectively treated with fluconazole alone.
Area of Science:
- Urology
- Infectious Diseases
- Immunology
Background:
- Behçet's disease is a multisystem inflammatory disorder.
- Prostate infections are uncommon but can cause significant urinary symptoms.
- Cryptococcus neoformans is an opportunistic fungal pathogen.
Observation:
- A 55-year-old male with Behçet's disease experienced acute urinary retention.
- Imaging and cultures confirmed Cryptococcus neoformans infection localized to the prostate.
Findings:
- The patient's acute urinary retention resolved completely with antifungal therapy.
- Fluconazole monotherapy was sufficient for treating the localized prostatic cryptococcosis.
- No evidence of systemic or recurrent local infection was observed at 32 months post-treatment.
Implications:
- This case highlights a rare presentation of prostatic cryptococcosis in an immunocompromised patient.
- Antifungal treatment, specifically fluconazole, can be effective for localized prostatic fungal infections.
- Early diagnosis and targeted therapy are crucial for favorable outcomes in such cases.