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Published on: October 18, 2018
Evolving asymmetric hypertrophic pyloric stenosis associated with histologic evidence of eosinophilic gastroenteritis
F G Blankenberg1, B R Parker, E Sibley
1Department of Radiology, Lucile Salter Packard Children's Hospital, Stanford Medical Center, Palo Alto, CA 94304, USA.
Insights
Infantile hypertrophic pyloric stenosis (IHPS) is a common cause of gastric outlet obstruction. Eosinophilic gastroenteritis may contribute to IHPS, suggesting endoscopy is a valuable diagnostic tool.
Area of Science:
- Pediatric Gastroenterology
- Neonatal Surgery
Background:
- Infantile hypertrophic pyloric stenosis (IHPS) is the primary cause of gastric outlet obstruction in infants.
- A potential link between IHPS and eosinophilic gastroenteritis warrants further investigation into their etiologic relationship.
Observation:
- Sonographic findings in IHPS, such as pyloric muscular wall thickness, may be influenced by allergic gastroenteropathy.
- Endoscopy has been suggested as a more reliable diagnostic method than sonography for evolving IHPS.
Findings:
- This study supports previous findings suggesting a connection between IHPS and eosinophilic gastroenteritis.
- The degree and duration of allergic gastroenteropathy could play a role in the sonographic presentation of IHPS.
Implications:
- Understanding the potential role of allergic conditions in IHPS may refine diagnostic approaches.
- Endoscopic evaluation may be crucial for accurate diagnosis in complex or evolving IHPS cases.
Abstract:
The most frequently occurring and important cause of gastric outlet obstruction in the neonate and young infant is infantile hypertrophic pyloric stenosis (IHPS). A reported association of IHPS and eosinophilic gastroenteritis [1] raises interesting questions about the possible etiologic relationship between the two entities. It is plausible that the observed sonographic pyloric muscular wall thickness in IHPS may in part be dependent on the degree and duration of an allergic gastroenteropathy. A recent report suggests that endoscopy may be a more reliable diagnostic method than sonography in the patient with evolving IHPS [2]. Our recent experience with a patient with evolving IHPS supports the findings described in these prior reports.
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