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Alphanumeric sequencing and cognitive impairment among elderly persons

J Grigsby1, K Kaye

  • 1Department of Medicine, University of Colorado Health Sciences Center, Denver 80222, USA.

Perceptual and Motor Skills
|June 1, 1995
PubMed
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Alphanumeric Sequencing, a cognitive test, showed poorer performance in older VA patients with lower scores on the Mini-Mental State Examination or Behavioral Dyscontrol Scale. This indicates its utility in assessing cognitive function in geriatric populations.

Area of Science:

  • Geriatric Medicine
  • Neuropsychology
  • Cognitive Assessment

Background:

  • Alphanumeric Sequencing (AS) involves alternating recitation of numbers and letters.
  • Cognitive decline is prevalent in aging populations, necessitating reliable assessment tools.
  • The study evaluates AS in a geriatric cohort, specifically U.S. Veterans Affairs (VA) patients.

Purpose of the Study:

  • To assess the utility of Alphanumeric Sequencing as a cognitive measure in older adults.
  • To investigate the correlation between Alphanumeric Sequencing performance and other established neuropsychological tests.
  • To identify demographic or clinical factors associated with Alphanumeric Sequencing performance.

Main Methods:

  • 112 VA patients aged 61-100 years were administered Alphanumeric Sequencing.

Related Experiment Videos

  • Participants also completed the Trail Making Test, Digits Forward and Backward, Mini-Mental State Examination (MMSE), and Behavioral Dyscontrol Scale (BDS).
  • Performance on Alphanumeric Sequencing was analyzed in relation to scores on other cognitive and behavioral measures.

    • Main Results:

    • Poorer Alphanumeric Sequencing performance was observed in patients scoring below 27 on the MMSE or below 14 on the BDS.
    • Alphanumeric Sequencing time and error scores showed significant correlations (ranging from .11 to -.49) with measures of information processing and short-term memory.
    • These findings suggest Alphanumeric Sequencing is sensitive to cognitive impairment in older adults.

    Conclusions:

    • Alphanumeric Sequencing is a valuable tool for assessing cognitive function in elderly VA patients.
    • Impaired performance on Alphanumeric Sequencing is associated with lower scores on global cognitive and behavioral assessments.
    • The test's correlations with information processing and memory measures highlight its relevance in neuropsychological evaluations.