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Posterior circulation in moyamoya disease: angiographic study
1Department of Radiology, Faculty of Medicine, Tokyo Medical and Dental University, Japan.
Radiology
|October 1, 1995
Summary
Moyamoya disease commonly affects posterior circulation, with stenotic lesions in the posterior cerebral arteries (PCAs) increasing alongside internal carotid artery (ICA) disease. This progression correlates with higher rates of cerebral infarction.
Area of Science:
- Neurology
- Vascular Neurology
- Neuroimaging
Background:
- Moyamoya disease is a rare cerebrovascular disorder.
- It is characterized by progressive stenosis of the internal carotid arteries (ICAs) and the circle of Willis.
- Posterior circulation involvement is less understood.
Purpose of the Study:
- To elucidate the angiographic characteristics of the posterior circulation in patients diagnosed with moyamoya disease.
- To correlate posterior circulation findings with anterior circulation disease and parenchymal changes.
Main Methods:
- Conventional angiography was performed on 76 patients with idiopathic moyamoya disease.
- Angiographic findings, including steno-occlusive lesions and collateral vessels, were analyzed.
- Results were compared with parenchymal lesions identified via CT and MRI.
Main Results:
- Steno-occlusive lesions were identified in 66 of 152 posterior cerebral arteries (PCAs) (43%).
- The incidence of PCA lesions significantly correlated with the severity of internal carotid artery (ICA) bifurcation stenosis.
- Increased ICA stenosis was associated with more basal and transdural collaterals, but fewer leptomeningeal collaterals, alongside a rise in PCA lesions.
Conclusions:
- Steno-occlusive lesions in the PCA are more frequent as ICA bifurcation stenosis worsens.
- The extent of PCA lesions is directly associated with an increased frequency of cerebral infarctions.