Graphical models for panel studies, illustrated on data from the Framingham Heart Study
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Updated: Oct 24, 2026

Patient-specific Modeling of the Heart: Estimation of Ventricular Fiber Orientations
Published on: January 8, 2013
J P Klein1, N Keiding, S Kreiner
1Division of Biostatistics, Medical College of Wisconsin, Milwaukee 53226, USA.
Abstract:
Recursive graphical models allow description of the simultaneous development of several (discrete) characteristics such as are recorded in a panel study. Irreversible events (death, irreversible disease occurrence) between exams are naturally included. This paper reviews these models and gives a detailed discussion of an example consisting of 49-50 year old males from the Framingham Heart study. The program DIGRAM is used throughout and the present paper may also serve as an introduction to this software.
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