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Updated: Sep 26, 2026

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
Published on: January 9, 2015
Management of obsessive compulsive disorder
1Institute of Mental Health/Woodbridge Hospital, Singapore.
Abstract:
The treatment of obsessive compulsive disorder was characterised by therapeutic pessimism until 25 years ago when effective treatments using behaviour therapy and the serotonin reuptake inhibitors were developed. At present the best available treatment is a combination of behaviour therapy and pharmacotherapy with a serotonin reuptake inhibitor. Psychosurgery is only indicated for patients who fail to respond to pharmacologic and behavioural treatments and who suffer from disabling symptoms.
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