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[A case of melorheostosis with linear sclerodermatous skin changes]
1Department of Internal Medicine II, School of Medicine, Hokkaido University, Sapporo-city.
Ryumachi. [Rheumatism]
|June 1, 1995
Summary
Melorheostosis, a rare bone disorder, can cause sclerodermatous skin changes. This case highlights melorheostosis as a potential cause of thickened skin and joint pain, distinct from linear scleroderma.
Area of Science:
- Orthopedics
- Dermatology
- Radiology
Background:
- Melorheostosis is a rare, benign, non-inherited bone disease characterized by irregular, dense bone formation.
- Sclerodermatous skin changes can occur in various conditions, including linear scleroderma.
Observation:
- A 69-year-old woman presented with chronic left elbow pain and progressive skin thickening of the upper limb.
- Radiographs revealed cortical hyperostosis from the humerus to the radius, with increased bone scintigraphy uptake.
- Skin biopsy showed collagen fiber proliferation without inflammation, suggesting a non-scleroderma cause.
Findings:
- The patient was diagnosed with melorheostosis based on radiographic and scintigraphic findings.
- The sclerodermatous skin changes were attributed to the underlying melorheostosis, not linear scleroderma.
Implications:
- This case suggests melorheostosis should be considered in the differential diagnosis of sclerodermatous skin changes.
- Recognizing melorheostosis as a cause of skin manifestations can lead to appropriate diagnosis and management.